MOTS-C

MOTS-C Peptide

MOTS-c (mitochondrial open-reading-frame of the 12S rRNA-c) is a 16 amino acid peptide classified as a Mitochondrial-Derived Peptide (MDP), aka “mitochondrial hormone” or “mitokine.” Recent research indicates that MOTS-c is a bioactive peptide closely associated with mitochondrial communication and energy regulation. Initially, researchers hypothesized that it might be most active in the mitochondria, however recent studies suggest otherwise, that MOTS-c may operate via the bloodstream, exhibiting a potentially systemic action.

It is important to note that MOTS-c is a newly identified MDP. Its primary roles are under investigation, but studies include MOTS-c peptide’s influence in cell function and longevity, muscle contractile force, metabolic function and weight regulation.