ACTH 1-39

ACTH 1-39 is a synthetic form of the endogenous pituitary hormone extensively used in pre-clinical research to investigate melanocortin-2 receptor (MC2R) activation, cAMP-mediated steroidogenesis, adrenal growth dynamics, and HPA axis feedback loops. This research-grade peptide is produced under stringent GMP-compliant conditions and provided as a lyophilized powder to ensure superior purity, stability, and reliability in experimental applications.

Engineered solely for preclinical investigations, each batch of ACTH (1-39) undergoes a comprehensive quality assessment and includes complete documentation, including a Certificate of Analysis (COA), purity data, and structural verification.

Scientific Overview

ACTH 1-39 binds MC2R on adrenocortical cells to stimulate glucocorticoid production via adenylyl cyclase and cAMP pathways in research settings. Preclinical literature has investigated ACTH (1-39) in the following areas of laboratory study:

• Cortisol and corticosterone biosynthesis pathways in adrenal cortex models
• Adrenal growth and zona fasciculata maintenance mechanisms
• Stress-induced steroidogenic enzyme expression in experimental models
• Oligodendroglial progenitor proliferation and differentiation in CNS cell culture models
• HPA axis dynamics and glucocorticoid feedback in pre-clinical study designs